Lab Results - Oct-Dec, 2019

  Lab Results  - Pre-Lemtrada and Post-Lemtrada Oct-Dec, 2019

Lemtrada can cause a variety of issues and secondary auto-immune diseases. Monthly blood and urine tests are done to try and spot things early.  Patients are also instructed to do self-checks and look out for things like lumps, red spots on our skin, changes in urine color, bruising, etc.  There are other things like fever and stomach issues that could point to an infection as well.  A CBC or Complete Blood Count is done to check for Immune Thrombocytopenia (ITP, or low platelets); white blood cells for signs of infection and your Lymphocytes to see how your immune system is coming back.  My doctor also does a Lymphocyte Subset to see where your T cells and B cells are in comparison to each other.  He tries to make sure they come "on-line" together.  Liver issues like autoimmune hepatitis is possible; alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are the common enzymes they check for.  Thyroid disease is a common side effect so Thyroid Stimulating Hormone (TSH) is part of the protocol.  Kidney function is checked in both the urine test (protein levels) and blood, glomerular filtration rate (GFR)  (how well your kidneys are filtering out Creatinine). 

Below are the more important levels in my monthly blood results.   
Last month the lab was unable to determine my T&B cell levels and this month I have not received those results or my metabolic panel.  I am not sure if the hold up is the holidays but I'll enter them when and if I receive them.

A couple of notes: In September, I had just had a UTI so that's why my white blood cell/Lymphocyte count is high.  The results in October are 1-week post-Lemtrada and were done because I had a change in urine color so not all the blood tests were done.

Results updated: 01/07/2020

	Ref Range	Pre-Lemtrada	Post Lemtrada
		9/29/19	10/25/19	11/20/19	12/19/19
Blood
White Blood Cell	3.8-10.8	10.9	8	5.7	6.8
Red Blood Cell	3.8-5.1	5.04	5.12	4.79	4.25
Platelet Count	140-400	193	213	163	182
Absolute Lymphocytes	850-3900	3793	80	382	374
Lymphocytes Subset
%CD3 (Mature T Cells)	57-85	78	N/A	TNP	19
Absolute CD3+	840-3060	3206			76
%CD4 (Helper T Cells)	30-61	53			11
Absolute CD4+	490-1740	2222			46
%CD8+ ("Killer" T Cells)	12-42	23			8
Absolute CD8+	180-1170	975			34
CD4/CD8 Ratio	0.86-5.00	2.28			1.35
%CD19 (B Cells)	6-29	11			34
Absolute CD19+	110-660	437			136
Absolute Lymphocytes	850-3900	4121			403
Liver Function
AST	10-30		16	18	12
ALT	6-29		12	8	4
Thyroid Function
TSH	0.4-4.5	1.61	NA	1.44	1.62
Kidney Function
eGFR	>60	105	88	88	92