Lab Results Jan - Mar 2020

  Lab Results  - Pre-Lemtrada and Post-Lemtrada Jan-Mar, 2020

Lemtrada can cause a variety of issues and secondary auto-immune diseases. Monthly blood and urine tests are done to try and spot things early.  Patients are also instructed to do self-checks and look out for things like lumps, red spots on our skin, changes in urine color, bruising, etc.  There are other things like fever and stomach issues that could point to an infection as well.  A CBC or Complete Blood Count is done to check for Immune Thrombocytopenia (ITP, or low platelets); white blood cells for signs of infection and your Lymphocytes to see how your immune system is coming back.  My doctor also does a Lymphocyte Subset to see where your T cells and B cells are in comparison to each other.  He tries to make sure they come "on-line" together.  Liver issues like autoimmune hepatitis is possible; alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are the common enzymes they check for.  Thyroid disease is a common side effect so Thyroid Stimulating Hormone (TSH) is part of the protocol.  Kidney function is checked in both the urine test (protein levels) and blood, glomerular filtration rate (GFR)  (how well your kidneys are filtering out Creatinine). 

Below are the more important levels in my monthly blood results.  

A note: In September 2019, I had just recovered from a UTI so that's why my white blood cell/Lymphocyte count is high. 

	Ref Range	Pre-Lemtrada	Post Lemtrada
		9/29/19	1/16/20	2/18/20	3/17/20
Blood
White Blood Cell	3.8-10.8	10.9	6.2	7.3	8.2
Red Blood Cell	3.8-5.1	5.04	4.2	4.5	4.64
Platelet Count	140-400	193	152	161	157
Absolute Lymphocytes	850-3900	3793	583	562	853
Lymphocytes Subset
%CD3 (Mature T Cells)	57-85	78	15	15	16
Absolute CD3+	840-3060	3206	86	84	134
%CD4 (Helper T Cells)	30-61	53	10	10	10
Absolute CD4+	490-1740	2222	51	52	72
%CD8+ ("Killer" T Cells)	12-42	23	7	5	7
Absolute CD8+	180-1170	975	37	29	47
CD4/CD8 Ratio	0.86-5.00	2.28	1.39	1.8	1.52
%CD19 (B Cells)	6-29	11	45	53	32
Absolute CD19+	110-660	437	281	299	299
Absolute Lymphocytes	850-3900	4121	580	559	816
Liver Function
AST	10-30		14	11	18
ALT	6-29		7	7	7
Thyroid Function
TSH	0.4-4.5	1.61	0.58	1.22	0.71
Kidney Function
eGFR	>60	105	97	88	76